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Chair of Neurology · Rambam Health Care Campus

Prof. Shahar Shelly

Neurologist · Neuromuscular & Neuroimmunology Specialist
“World class expertise. Personal, attentive care.”

Prof. Shahar Shelly is one of Israel's leading neurologists, specializing in neuromuscular diseases and neuroimmunology. After completing his neurology residency with distinction at Sheba Medical Center, Tel HaShomer, he undertook a fellowship at Mayo Clinic (2018–2021), where he and his colleagues discovered the antibody responsible for neurochondrin-associated ataxia — a finding now used worldwide for the diagnosis of malignancies. In 2024, Prof. Shelly was appointed Chair of the Department of Neurology at Rambam Health Care Campus, home to the largest neuromuscular unit in northern Israel. He also serves as Full Professor at the Technion and directs a research laboratory integrating artificial intelligence with clinical neurology.

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Mayo Clinic Fellowship
Top 10 Neurologist (Doximity)
80+ Publications
Rambam Chair of Neurology
Prof. Shahar Shelly, Neurologist
Prof. Shahar Shelly
Neurologist · Rambam | Technion | Mayo Clinic
Academic & Clinical Affiliations
Rambam Health Care Campus
Technion Faculty of Medicine
Mayo Clinic
🔬
RTICC – Rappaport Cancer Center
🧠
Israeli Neurological Society
🌍
World Org. for Congenital Muscular Diseases
About Prof. Shelly

A Physician, Researcher & Innovator

Prof. Shahar Shelly is a leading Israeli neurologist specializing in neuromuscular diseases and neuroimmunology. After completing his medical degree with distinction at the University of Debrecen, he trained in neurology at Sheba Medical Center and pursued a prestigious fellowship at Mayo Clinic (2018–2021), where he co-discovered the antibody responsible for neurochondrin-associated ataxia — now used in routine malignancy screening worldwide.

In 2024 he was appointed Chair of the Neurology Department at Rambam — the largest neuromuscular unit in northern Israel — while continuing his role as Head of Neuroimmunology at the Technion and directing the AI Neurology Laboratory, which integrates machine learning with clinical neuroscience.

  • University of Debrecen
    Medical Degree
    University of Debrecen, Hungary — with Distinction
  • Mayo Clinic
    Fellowship
    Mayo Clinic · Neuromuscular & Electrophysiology (2018–2021)
  • 🌍
    International Role
    Mediterranean Basin Representative, World Org. for Congenital Muscular Diseases (2023)
  • ⚗️
    Entrepreneurship
    Medical Director, Remepy — digital-pharma hybrid startup ($15M raised)
Career Timeline

Training & Positions

University of Debrecen
2005 – 2012
Medical Degree
University of Debrecen, Hungary — with Distinction
Sheba Medical Center
2013 – 2017
Neurology Residency
Sheba Medical Center (Tel HaShomer)
Mayo Clinic
2018 – 2021
Fellowship — Mayo Clinic
Neuromuscular Diseases & Electrophysiology, Rochester MN
Rambam
2022 – present
Head, Neuromuscular Division — Rambam
Largest neuromuscular unit in northern Israel
Technion
2022 – present
Head of Neuroimmunology & AI Neurology Lab — Technion
Integrating ML, big data & clinical neuroscience
Rambam
April 2024
Chair, Department of Neurology — Rambam
Leading the full spectrum of neurological care
Medical Specialties

Areas of Expertise

Comprehensive care across the full spectrum of neuromuscular and neuroimmunological conditions, supported by advanced electrophysiology diagnostics.

Neuromuscular Diseases

Polyneuropathy, CIDP, ALS, myasthenia gravis, inflammatory muscle diseases, and hereditary neuromuscular conditions.

Neuroimmunology

Autoimmune neurological diseases, paraneoplastic neuropathies, neuro-oncology-related nerve disorders, and immunotherapy-related complications.

Clinical Electrophysiology

EMG, nerve conduction studies, and advanced electrophysiological evaluation of peripheral nerve and muscle disorders.

Peripheral Nerve Disorders

Small fiber neuropathy, autoimmune nodopathies, peripheral nerve hyperexcitability disorders, and inflammatory nerve diseases.

AI in Neurology

Machine learning based diagnostic support, AI driven neurophysiology models, and predictive clinical decision tools for neurological emergencies.

Genetic & Rare Diseases

Genetic counseling for neuromuscular diseases, oculopharyngeal muscular dystrophy, and rare hereditary neurological conditions.

Sub-Specialty

Myasthenia Gravis Expert

Myasthenia gravis (MG) is an autoimmune disease where the immune system mistakenly attacks the connection between nerves and muscles. This causes muscles to tire quickly — leading to drooping eyelids, double vision, difficulty swallowing or speaking, and in some cases serious breathing problems.

Prof. Shelly is one of Israel's leading MG specialists. He led the writing of Israel's first national clinical guidelines for MG, has published over 13 peer reviewed papers on the disease, co-authored an editorial in the New England Journal of Medicine, and treats complex MG patients at both Rambam and his private clinic.

✓
Accurate Diagnosis
Including antibody testing algorithms developed at Mayo Clinic to reduce misdiagnosis.
✓
Personalised Treatment
From standard immunosuppression to the newest FDA-approved biologic therapies (efgartigimod, rituximab).
✓
Multidisciplinary Care
Coordinating with thoracic surgeons, oncologists, and pulmonologists for comprehensive management.
📅 Book an MG Consultation
Peer reviewed Research

MG Research Highlights

Selected publications — explained in plain language.

Editorial: Redemption for B-Cell Depletion in MG
Written with leading MG expert Prof. Gil Wolfe — published in the New England Journal of Medicine (2025). In plain terms: drugs that "switch off" specific immune cells show great promise for controlling MG long term.
2025 · New England Journal of Medicine
Israel's National Guidelines for MG Diagnosis & Treatment
Led by Prof. Shelly — the first official Israeli roadmap for how every neurologist in the country should diagnose and treat MG, tailored to each patient's antibody type and disease severity.
2025 · Therapeutic Advances in Neurological Disorders
Real world Results: Efgartigimod in MG Patients
86% of MG patients improved significantly after the first treatment cycle of efgartigimod — a new drug that "mops up" the harmful antibodies causing MG — and many were able to reduce their steroid doses.
2024 · Journal of Neurology
Smarter Blood Tests: Reducing MG Misdiagnosis by 45%
A new sequential testing algorithm developed at Mayo Clinic dramatically reduces false positive MG diagnoses — meaning fewer patients go through unnecessary treatments for a disease they don't have.
2020 · Neurology
Thymectomy (Thymus Surgery) Improves Survival in MG
MG patients who had their thymus gland surgically removed had the best survival outcomes, with zero deaths in that group — supporting surgery as a highly beneficial treatment option for eligible patients.
2025 · Frontiers in Immunology
Private Clinic

Shelly Clinic Center

A leading private diagnostic center specializing in neuromuscular and peripheral nervous system disorders — offering rapid, expert level diagnosis and multidisciplinary care in a patient centered environment.

📍 42–44 Nathan Alterman St., Herzliya, Ground Floor
📞 09-9656565
📅 Schedule an Appointment
01

Neurological Consultation

Advanced diagnosis and treatment of peripheral nerve and muscle disorders.

02

EMG Testing

Electromyography and nerve conduction studies for precise neuromuscular diagnosis.

03

Genetic Counseling

Genetic diagnosis for neuromuscular, epilepsy, and developmental disorders.

04

Physical Therapy

Specialized rehabilitation programs for neuromuscular and neurological conditions.

Research

AI Neurology Lab & Research Focus

Prof. Shelly directs the AI Neurology Laboratory at the Technion, integrating machine learning, big data analytics, and multimodal data to develop predictive models and clinical decision support tools for neurological diseases.

1

Biological Markers for Neurological Diseases & Cancer

Identifying novel biomarkers to improve early detection and monitoring of neuromuscular and neuro-oncological conditions.

2

Cancer Immunotherapy & the Nervous System

Investigating the effects of immune checkpoint inhibitors and other immunotherapies on peripheral nerves and muscles.

3

Blood-Brain Barrier: Drugs & Nanoparticles

Studying how pharmacological agents and nanoparticle-based therapies interact with and cross the blood-brain barrier.

Selected Publications

Recent Research

Over 80 peer reviewed publications. Multiple patents.

AI-generated neurology consultation summaries improve efficiency in the emergency department
2025 · Journal of Neurology
AI based Clinical Decision Making Tool for Neurologists in the Emergency Department
2025 · JMIR Neurotechnology
Twenty-Five Years of AI in Neurology: The Journey of Predictive Medicine and Biological Breakthroughs
2024 · JMIR Neurotechnology
Paraneoplastic neuropathies and peripheral nerve hyperexcitability disorders
2024 · Handbook of Clinical Neurology
Neurochondrin neurological autoimmunity — landmark antibody discovery
2019 · Neurology: Neuroimmunology & Neuroinflammation
View full publication list →
In the Press

Media Coverage

DOCTORS ONLY
21.08.2025

לראשונה בישראל: מאמר מערכת ב-NEJM מאת רופא ישראלי

פרופ׳ שחר שלי, מנהל מחלקת הנוירולוגיה ברמב״ם ויו״ר האגודה הישראלית למחלות עצב-שריר, פרסם יחד עם קולגה אמריקאי מאמר מערכת בכתב העת הרפואי היוקרתי ביותר בעולם — ה-NEJM — בנושא מיאסטניה גרביס. זהו הישג חסר תקדים לרופא ישראלי.

"פרסום המאמר משקף את עבודת צוות במרכז המצוינות למיאסטניה ברמב״ם. התחום מלא בחדשנות ומקיף קשת רחבה של מחלות."

— פרופ׳ שחר שלי
לכתבה המלאה ←
NEJM
New England
Journal of
Medicine
כתב העת הרפואי
המוביל בעולם
YNET NEWS
24.07.2026

AI System at Rambam Spots Critical ER Cases Within Seconds

The SHAKED system, developed by Prof. Shelly at Rambam, analyzes medical histories, lab results and imaging needs in real time — cutting admission delays by one hour and flagging hidden emergencies including a severe infection, suspected child abuse and a life-threatening potassium deficiency.

“This is the first AI system involved at highly important decision-making points in the emergency department. The results have already amazed us.”

— Prof. Shahar Shelly
Read Full Article →
🤖
SHAKED
AI Clinical Decision
Support System
▶ PODCAST

פודקאסט: "הכל בראש"

פרופ׳ שחר שלי מסביר כיצד המוח מעצב כל פן בחיינו — מתנועה ותחושה ועד רגש וחשיבה. שיחה מרתקת ונגישה המגשרת בין מדעי המוח לחיים עצמם.

▶ לצפייה ביוטיוב
Recognition

Awards & Honors

🏆
2021

Top 10 Most Influential Neurologists

Ranked among the ten most influential neurologists in research — Doximity.

🌟
2019

Young Promising Researcher Award

World Neurologists Association Congress — recognition for outstanding early career research contributions.

💡
2017

Milowitz Grant

Awarded to five most promising physicians of the future — in recognition of excellence in medicine and research.

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Pricing

Consultation Fees

Appointments are available on a private pay basis. Rates may vary depending on the type of consultation and procedures involved. Please contact our secretarial team for up to-date pricing information.

🧠

Neurological Consultation

First visit or follow up with Prof. Shelly. Includes full neurological history and examination.

Contact secretary for current rates
📋
Rates & Insurance Queries
Appointment rates may change. For the most current pricing, health fund coverage, and scheduling, please contact our secretary team directly.
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Get in Touch

Book a Consultation

To schedule an appointment at Shelly Clinic Center, or to reach Prof. Shelly's academic office at Rambam / Technion, use the contact information below.

📍
Clinic Address
42–44 Nathan Alterman St., Herzliya, Ground Floor
📞
Clinic Phone
09-9656565
🏥
Rambam Hospital
04-7773987
💬
WhatsApp
055-9669522
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